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Our findings shed light on the mechanism of action of LH-RH antagonists in BPH 45

Guanglin C, Hanzhe L, Gang X, Jann-Birger L, Zhigang P

PMID: 29948357

One way to circumvent this problem is the delivery of therapeutic genes encoding intracellular enzymes for the conversion of a prodrug to a cytotoxic drug which can then spread to neighboring non-transduced cells (bystander effect)